The relation between nutritional cholesterol and essential fatty acids and also the incidence of cancer of the lung was studied among 4,538 Finnish men aged 20–69 many initially free from cancer. During twenty years of follow‐up, 117 cancer of the lung cases were diagnosed. Cholesterol intake wasn’t connected with cancer of the lung risk, the age‐, smoking‐, and energy‐adjusted relative risk between your cheapest and greatest tertiles being 1. [95% confidence interval (CI) = .6–1.9]. The consumption of saturated essential fatty acids was nonsignificantly related to cancer of the lung incidence, the relative risk for that cheapest in contrast to the greatest fertile being 1.6 (CI = .8–3.2). The association was more powerful among smokers than among nonsmokers, the relative risks being 2.1 (CI = 1.0–4.3) and 1.3 (CI = .4–4.1), correspondingly. The relative risk among smokers, however, decreased to at least one.5 after adjustment for that amount they smoked. Within the total cohort, there is a considerably elevated chance of cancer of the lung among men having a high consumption of butter, among the primary causes of saturated essential fatty acids, the relative risk being 1.9 (CI = 1.1–3.2). The current data don’t confirm previous results suggesting that nutritional cholesterol predicts the appearance of cancer of the lung among men. The association between consumption of saturated essential fatty acids and cancer of the lung observed in our study might be partially because of heavy smoking among high consumers of saturated fats.