My spouse was identified as having Stage 2B cancer of the breast in Feb, 2016, and that i did a little bit of research about this subject. I’ll share my conclusions here, but please be aware that I’m a layman without any medical training whatsoever.
Stage 2B is really a heterogeneous mixture of specific kinds of cancer of the breast with different features, and also the detailed nuances of each patient’s disease matter Greatly in calculating a rate of survival.
The majority of the statistics (like the common 76% 5 year rate of survival) that I’ve located on the internet were calculated fifteen years ago from data collected in 2002–2003, meaning the treatments received (surgery, chemotherapy, radiation, hormonal therapies) were from Two decades ago.
GREAT strides in treatments happen to be made since that time.
The survival figures you’re studying now are most likely OLD and therefore are somewhat scarier compared to reality, that is still just a little frightening.
The very best calculator I’ve discovered ANYWHERE, that is a guide and just helpful information, is here now:
Cancer Of The Breast Outcome Calculator
When my spouse was diagnosed, I figured, in line with the couple of common survival #s I’d read at that time, “76% 5 year survival is awful. I must think fifteen years out, she’s maybe 50/50 at the best.” And That I felt like tossing up and completely helpless.
BUT, basically punch within my wife’s stats in to the above calculator:
Tumor Diameter: 3.4 cm
# of Positive Nodes: KNOWN 2
ER Status: Positive
PR Status: Positive
HER2 Status: Negative
Histological Type: Ductal
Grade: 2 – Moderately Diff.
The calculator spits the following:
“Classification: T2 N1 (pN1a) M0 AJCC Stage: IIB
Cancer Mortality:27.5% expected 15-year cancer dying rate.
(28.3% 15-year Kaplan-Meier cancer dying rate)”
From speaking to the oncologist, radiation oncologist, surgeon, yet others, individuals #s are most likely pretty near to accurate.. BUT Observe That Individuals #s ARE WITHOUT THERAPIES !!!
Hover on “Breast Cancer Tools” and click on THERAPY.
Within our situation, let’s add some following detail towards the above:
Hormonal Therapy: Tam to AI
Chemotherapy: DD CA*4 + T*4
Now hit UPGRADE GRAPH, and also the output reads:
“Classification: T2 N1 (pN1a) M0 AJCC Stage: IIB
Cancer Mortality:10.2% expected 15-year Cancer Dying Rate.
10.4% 15-year Kaplan-Meier cancer dying rate
The treatment selected would improve average existence expectancy by 6.three years, or 2310 days over expectancy without therapy.
69.4% less cancer deaths after 15 years”
This calculator doesn’t include advantages of radiotherapy, that is indicated for many 2B cases, and informally our radiation oncologist thinks that (regardless of the risks entailed of making other health issues), we may expect 15 year mortality to fall by half. That drops my wife’s 15 year cancer mortality to possibly 5%.
And something last little bit of great news. Should you browse the FAQs: CancerMath Calculator FAQ you will see the information is for 1987 through 2007: “All calculators tend against cancer patients diagnosed between 1987-2007 within the U . s . States Surveillance, Epidemiology and Finish-Results database. The cancer of the breast and melanoma calculators are also validated against a database of ~30,000 cancer of the breast and ~7,000 melanoma patients seen at Partners Hospitals” Treatments and outcomes have improved greatly in the mid-point proper diagnosis of 1997. Which was twenty years ago!
I’d finish using the following hopeful, yet careful, comments:
- Every situation differs. Literally everybody. And averages aren’t incredibly significant if you have just one data point and something existence.
- But averages are extremely useful in trying to puzzle out should you be turning over you have merely a couple of years left or that you’re most probably to enter permanent remission.
- Triple negative and HER2 positive patients have worse outcomes. Have fun with the inputs around the calculator to determine how altering the characteristics from the stage 2B cancer of the breast change outcomes.
- Outcomes for metastatic cancer of the breast continue to be inadequate. But outcomes for node positive stage 2B cancer of the breast, when you get with the surgery + chemotherapy + radiation + Tamoxifen and AI dental drugs, has surprisingly GOOD outcomes.
So keep the pull up. Concentrate on during your treatments, esp. the chemotherapy, that is tough. Live every single day. Bring your Tamox and AI pills every single day. And don’t forget that even if you’re within the small % of stage 2B patients having a bad outcome in 10 years… in ten years the treatments will improve still.
2B is an extremely serious diagnosis. However if you simply get all of your treatments, the chance are much better than the majority of the printed survival #s you’ll find on the internet.
I’ve attempted to create the above mentioned to become as accurate as you possibly can. Or no actual doctors or doctors resist anything I’ve written, please comment below, and i’m pleased to make changes to the inaccuracies or errors.